Oncology and Autoimmune Diseases
B1962
Indication——Advanced malignant solid tumors

Research Progress
Preclinical study was completed
Potential Advantages
(1) Can block the binding of PD-1 to PD-L1 to recover the function of T cells so that the immune system can kill tumor cells;
(2) Can block the binding between VEGF and VEGFR to degenerate the tumor vessels and normalize the surviving blood vessels to continuously inhibit angiogenesis, thereby achieving the control and treatment of tumors;
(3) Can target the tumor site to eliminate vascular epidermal growth factors in the tumor, thereby inhibiting the growth of new vessels at the tumor site effectively; better efficacy is expected in combination with anti-VEGF monoclonal antibodies (Avastin);
(4) A product yield of more than 6 g/L, which significantly improves the production capacity and reduces the production cost, thereby gaining competitiveness.